WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:positive regulation of heart contraction       ID:GO:0045823
C=23; O=2; E=0.03; R=57.83; rawP=0.0005; adjP=0.1386
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252


Database:biological process       Name:fat cell differentiation       ID:GO:0045444
C=130; O=3; E=0.20; R=15.35; rawP=0.0009; adjP=0.1386
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
2  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324
3  ENSG00000175602 NA CCDC85B coiled-coil domain containing 85B 11007 ENSG00000175602


Database:biological process       Name:heart process       ID:GO:0003015
C=135; O=2; E=0.20; R=9.85; rawP=0.0173; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252


Database:biological process       Name:muscle organ development       ID:GO:0007517
C=340; O=3; E=0.51; R=5.87; rawP=0.0138; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
3  ENSG00000179456 NA ZNF238 zinc finger protein 238 10472 ENSG00000179456


Database:biological process       Name:single-organism carbohydrate metabolic process       ID:GO:0044723
C=592; O=4; E=0.89; R=4.49; rawP=0.0109; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
2  ENSG00000100626 NA GALNTL1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 57452 ENSG00000100626
3  ENSG00000187486 NA KCNJ11 potassium inwardly-rectifying channel, subfamily J, member 11 3767 ENSG00000187486
4  ENSG00000172339 NA ALG14 asparagine-linked glycosylation 14 homolog (S. cerevisiae) 199857 ENSG00000172339


Database:biological process       Name:cellular protein modification process       ID:GO:0006464
C=2472; O=9; E=3.72; R=2.42; rawP=0.0067; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
2  ENSG00000165192 NA ASB11 ankyrin repeat and SOCS box containing 11 140456 ENSG00000165192
3  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
4  ENSG00000100626 NA GALNTL1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 57452 ENSG00000100626
5  ENSG00000114738 NA MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 7867 ENSG00000114738
6  ENSG00000172339 NA ALG14 asparagine-linked glycosylation 14 homolog (S. cerevisiae) 199857 ENSG00000172339
7  ENSG00000141279 NA NPEPPS aminopeptidase puromycin sensitive 9520 ENSG00000141279
8  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
9  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:biological process       Name:regulation of fat cell differentiation       ID:GO:0045598
C=64; O=2; E=0.10; R=20.78; rawP=0.0041; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324
2  ENSG00000175602 NA CCDC85B coiled-coil domain containing 85B 11007 ENSG00000175602


Database:biological process       Name:heart contraction       ID:GO:0060047
C=135; O=2; E=0.20; R=9.85; rawP=0.0173; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252


Database:biological process       Name:protein modification process       ID:GO:0036211
C=2472; O=9; E=3.72; R=2.42; rawP=0.0067; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
2  ENSG00000165192 NA ASB11 ankyrin repeat and SOCS box containing 11 140456 ENSG00000165192
3  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
4  ENSG00000100626 NA GALNTL1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 57452 ENSG00000100626
5  ENSG00000114738 NA MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 7867 ENSG00000114738
6  ENSG00000172339 NA ALG14 asparagine-linked glycosylation 14 homolog (S. cerevisiae) 199857 ENSG00000172339
7  ENSG00000141279 NA NPEPPS aminopeptidase puromycin sensitive 9520 ENSG00000141279
8  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
9  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:biological process       Name:glycosylation       ID:GO:0070085
C=265; O=3; E=0.40; R=7.53; rawP=0.0070; adjP=0.1719
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
2  ENSG00000100626 NA GALNTL1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 57452 ENSG00000100626
3  ENSG00000172339 NA ALG14 asparagine-linked glycosylation 14 homolog (S. cerevisiae) 199857 ENSG00000172339


Database:molecular function       Name:histone deacetylase binding       ID:GO:0042826
C=64; O=2; E=0.09; R=22.74; rawP=0.0034; adjP=0.0918
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:molecular function       Name:RNA polymerase II transcription factor binding       ID:GO:0001085
C=56; O=2; E=0.08; R=25.99; rawP=0.0026; adjP=0.0918
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:molecular function       Name:phosphatase activity       ID:GO:0016791
C=262; O=2; E=0.36; R=5.56; rawP=0.0496; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125458 NA NT5C 5', 3'-nucleotidase, cytosolic 30833 ENSG00000125458
2  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:molecular function       Name:sequence-specific DNA binding transcription factor activity       ID:GO:0003700
C=1009; O=4; E=1.39; R=2.89; rawP=0.0459; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
3  ENSG00000164900 NA GBX1 gastrulation brain homeobox 1 2636 ENSG00000164900
4  ENSG00000179456 NA ZNF238 zinc finger protein 238 10472 ENSG00000179456


Database:molecular function       Name:protein binding transcription factor activity       ID:GO:0000988
C=497; O=3; E=0.68; R=4.39; rawP=0.0294; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
3  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:molecular function       Name:enzyme binding       ID:GO:0019899
C=1086; O=4; E=1.49; R=2.68; rawP=0.0575; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
3  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
4  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:molecular function       Name:transcription coactivator activity       ID:GO:0003713
C=269; O=2; E=0.37; R=5.41; rawP=0.0520; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
2  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:molecular function       Name:carbohydrate binding       ID:GO:0030246
C=269; O=2; E=0.37; R=5.41; rawP=0.0520; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
2  ENSG00000100626 NA GALNTL1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 57452 ENSG00000100626


Database:molecular function       Name:nucleic acid binding transcription factor activity       ID:GO:0001071
C=1011; O=4; E=1.39; R=2.88; rawP=0.0462; adjP=0.3450
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
3  ENSG00000164900 NA GBX1 gastrulation brain homeobox 1 2636 ENSG00000164900
4  ENSG00000179456 NA ZNF238 zinc finger protein 238 10472 ENSG00000179456


Database:molecular function       Name:sequence-specific DNA binding       ID:GO:0043565
C=680; O=3; E=0.93; R=3.21; rawP=0.0643; adjP=0.3472
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000164900 NA GBX1 gastrulation brain homeobox 1 2636 ENSG00000164900
3  ENSG00000179456 NA ZNF238 zinc finger protein 238 10472 ENSG00000179456


Database:cellular component       Name:sarcolemma       ID:GO:0042383
C=91; O=2; E=0.14; R=14.42; rawP=0.0084; adjP=0.2388
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187486 NA KCNJ11 potassium inwardly-rectifying channel, subfamily J, member 11 3767 ENSG00000187486
2  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252


Database:cellular component       Name:nuclear chromosome       ID:GO:0000228
C=285; O=3; E=0.43; R=6.90; rawP=0.0090; adjP=0.2388
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000164900 NA GBX1 gastrulation brain homeobox 1 2636 ENSG00000164900
3  ENSG00000179456 NA ZNF238 zinc finger protein 238 10472 ENSG00000179456


Database:cellular component       Name:cell-substrate junction       ID:GO:0030055
C=143; O=2; E=0.22; R=9.17; rawP=0.0199; adjP=0.2388
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196923 NA PDLIM7 PDZ and LIM domain 7 (enigma) 9260 ENSG00000196923
2  ENSG00000171368 NA TPPP tubulin polymerization promoting protein 11076 ENSG00000171368


Database:cellular component       Name:focal adhesion       ID:GO:0005925
C=131; O=2; E=0.20; R=10.01; rawP=0.0169; adjP=0.2388
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196923 NA PDLIM7 PDZ and LIM domain 7 (enigma) 9260 ENSG00000196923
2  ENSG00000171368 NA TPPP tubulin polymerization promoting protein 11076 ENSG00000171368


Database:cellular component       Name:cell-substrate adherens junction       ID:GO:0005924
C=136; O=2; E=0.21; R=9.65; rawP=0.0181; adjP=0.2388
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196923 NA PDLIM7 PDZ and LIM domain 7 (enigma) 9260 ENSG00000196923
2  ENSG00000171368 NA TPPP tubulin polymerization promoting protein 11076 ENSG00000171368


Database:cellular component       Name:adherens junction       ID:GO:0005912
C=201; O=2; E=0.31; R=6.53; rawP=0.0373; adjP=0.3630
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196923 NA PDLIM7 PDZ and LIM domain 7 (enigma) 9260 ENSG00000196923
2  ENSG00000171368 NA TPPP tubulin polymerization promoting protein 11076 ENSG00000171368


Database:cellular component       Name:anchoring junction       ID:GO:0070161
C=218; O=2; E=0.33; R=6.02; rawP=0.0432; adjP=0.3630
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196923 NA PDLIM7 PDZ and LIM domain 7 (enigma) 9260 ENSG00000196923
2  ENSG00000171368 NA TPPP tubulin polymerization promoting protein 11076 ENSG00000171368


Database:cellular component       Name:cytoplasmic part       ID:GO:0044444
C=6772; O=15; E=10.32; R=1.45; rawP=0.0484; adjP=0.3630
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
2  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
3  ENSG00000100626 NA GALNTL1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 57452 ENSG00000100626
4  ENSG00000140750 NA ARHGAP17 Rho GTPase activating protein 17 55114 ENSG00000140750
5  ENSG00000114738 NA MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 7867 ENSG00000114738
6  ENSG00000172339 NA ALG14 asparagine-linked glycosylation 14 homolog (S. cerevisiae) 199857 ENSG00000172339
7  ENSG00000175602 NA CCDC85B coiled-coil domain containing 85B 11007 ENSG00000175602
8  ENSG00000141279 NA NPEPPS aminopeptidase puromycin sensitive 9520 ENSG00000141279
9  ENSG00000122378 NA FAM213A family with sequence similarity 213, member A 84293 ENSG00000122378
10  ENSG00000125458 NA NT5C 5', 3'-nucleotidase, cytosolic 30833 ENSG00000125458
11  ENSG00000167676 NA PLIN4 perilipin 4 729359 ENSG00000167676
12  ENSG00000187486 NA KCNJ11 potassium inwardly-rectifying channel, subfamily J, member 11 3767 ENSG00000187486
13  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
14  ENSG00000171368 NA TPPP tubulin polymerization promoting protein 11076 ENSG00000171368
15  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:cellular component       Name:transcription factor complex       ID:GO:0005667
C=291; O=2; E=0.44; R=4.51; rawP=0.0721; adjP=0.4326
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166337 NA TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 6881 ENSG00000166337
2  ENSG00000134324 NA LPIN1 lipin 1 23175 ENSG00000134324


Database:cellular component       Name:chromosome       ID:GO:0005694
C=626; O=3; E=0.95; R=3.14; rawP=0.0685; adjP=0.4326
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135547 NA HEY2 hairy/enhancer-of-split related with YRPW motif 2 23493 ENSG00000135547
2  ENSG00000164900 NA GBX1 gastrulation brain homeobox 1 2636 ENSG00000164900
3  ENSG00000179456 NA ZNF238 zinc finger protein 238 10472 ENSG00000179456




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).